DNA

There are so many different test's currently on the market that it can be overwhelming knowing which one to choose.

By discussing your goals with our team, we'll be able to guide you towards the most appropriate package. Be that based on price, extensiveness of testing, depth of reporting, mobile applications or turn around time. 

Below contains a list of the different aspects we're able to assess by decoding your genetics. Most of these tests aren't sold individually, but instead in combination.

 

Detoxification


This test evaluates SNPs associated with increased risk of impaired detoxification capacity especially when exposed to environmental toxins. It also identifies individuals potentially susceptible to adverse drug reactions. Please contact us for pricing




Allergies & Sensitivites


Assess your DNA-based predisposition to allergies and sensitivities such as gluten sensitivity, lactose intolerance, pet and plant allergies, sensitivity to mercury and benzene, motion sickness and many others.

  • Food Allergies
  • Indoor Allergies
  • Outdoor Allergies
  • Sensitivity to Chemicals
  • Other Sensitivities
Please contact us for pricing




Estrogen


The Estrogenomic Profile uses genomic testing to identify susceptibility to diseases and conditions such as breast cancer, osteoporosis, and heart disease. More specifically, the EstroGenomic Profile evaluates genetic variations, called single nucleotide polymorphisms (SNPs) in genes that modulate estrogen metabolism, coagulation, cardiovascular function, bone health, and inflammation. The Estrogenomic test uncovers potential genetic susceptibility to diseases and conditions such as:

  • Breast cancer
  • Osteoporosis
  • Thrombosis
  • Strokes
  • Atherosclerosis
  • Heart Disease
Specialized genomic testing from Genova Diagnostics can provide a glimpse into ones potential health future. Genetic testing enables one to minimize the risk by:
  • Identifying hidden gene mutations that may promote chronic disease
  • Preventing disease through early intervention
  • Modifying gene expression through more precise, targeted, individualized interventions
  • Identifying key areas for follow-up testing
  • Monitoring therapeutic effectiveness of intervention strategies with laboratory testing
Whether or not you choose to see genes, they are always there and will continue to play an important role in one's health. With genomic testing, by choosing to look at them, you have the opportunity to influence the ultimate outcome and more actively promote a healthy life. The EstroGenomic® Profile evaluations include: Estrogen Metabolism
  • CYP1A1
  • GST (M1 and P1)
  • CYP1B1
  • COMT (catechol-O-methyl transferase)
Estrogen metabolism SNPs focus on the Phase 1 enzymes involved in the formation of anti- or procarcinogenic metabolites such as 2-hydroxyestrone and 4-hydroxyestrone, respectively, as well as the Phase 2 enzymes responsible for the subsequent metabolism of these compounds. Levels of the various estrogen metabolites modulate risk of both breast cancer and osteoporosis. HyperCoagulation
  • GP3a (Glycoprotein 3)
  • Factor 2 (Prothrombin)
  • PAI-1 (Plasminogen activator inhibitor-1)
  • Factor 5 (Leiden)
These genetic variants focus on estrogens interaction with some of the key constituents of the clot formation and fibrinolysis process, such as clotting factors and inhibitors of fibrinolysis. The SNPs can over-activate blood clotting processes, increasing the risk of sudden cardiac events such as thrombosis, heart attacks, and strokes, especially among women take supplemental estrogens and oral contraceptives. Cardiovascular
  • Apo E (apoliprotein E)
  • TNF-a
  • MTHFR
  • IL-6
These genes affect how the body processes cholesterol, responds to inflammation, and metabolizes B vitamins. The presence of these SNPs can increase risk of cardiovascular disease, hyperlipidemia, and blood vessel damage.
  • Osteoporosis
  • VDR
  • TNF-a
  • IL-6
Osteoporosis SNPs relate to estrogens influence on inflammation, bone resorption, vitamin D function and bone collagen formation. Test Type: Saliva Test Please contact us for pricing




Immune & Inflammatory Activity


This test evaluates genetic variations in genes that modulate immune and inflammatory activity. These variations can affect balance between cell (Th-1) and humoral (Th-2) immunity, trigger potential defects in immune system defense, and stimulate mechanisms underlying chronic, overactive inflammatory responses. Please contact us for pricing




Neuro Genomics


Advances in human neurogenetics have begun to shed light on the genomic architecture of complex diseases of mood, cognition, brain development, and neurodegeneration. From genome-wide association studies to rare variants, these findings hold promise for defining the pathogenesis of brain disorders that have resisted simple molecular description. This test evaluates single nucleotide polymorphisms (SNPs) in genes that modulate methylation, glutathione conjugation, oxidative protection and the potential to evaluate vascular oxidation. Please contact us for pricing




Cardio Vascular Health


This profile analyzes blood and utilizes NMR fractionation technology for state-of-the-art lipid markers and independent risk factors that illuminate the clinical complexity of cardiovascular disease (CVD) as well as a patient's genomic predisposition to cardiovascular diseases. Together, these markers provide a thorough assessment of cardiovascular health status, revealing the biochemical environment and cardiogenomic risk associated with inflammation, lipid deposits, endothelial dysfunction, and clotting factors underlying cardiovascular disease. The Cardio Genomic Profile uses genomic testing to identify the risk of genetic susceptibility to cardiac related diseases and conditions. Specifically, the the CardioGenomic Profile evaluates genetic variations, called single nucleotide polymorphisms (SNPs) in genes that modulate blood pressure regulation, lipid balance, nutrient metabolism, inflammation, and oxidative stress. This test uncovers potential genetic susceptibility to:

  • Hypercholesteremia
  • Atherosclerosis
  • Obesity
  • Hypertension
  • Myocardial infarction
  • Thrombosis
  • Endothelial dysfunction
  • Stroke
Specialized genomic testing can provide a glimpse into ones potential health future. Genetic testing enables one to minimize the risk by:
  • Identifying hidden gene mutations that may promote chronic disease
  • Preventing disease through early intervention
  • Modifying gene expression through more precise, targeted, individualized interventions
  • Identifying key areas for follow-up testing
  • Monitoring therapeutic effectiveness of intervention strategies with laboratory testing
Whether or not you choose to see genes, they are always there and will continue to play an important role in one's health. With genomic testing, by choosing to look at them, you have the opportunity to influence the ultimate outcome and more actively promote a healthy life. The Cardio Genomic Profile evaluations include: Cholesterol Regulation and Atherosclerosis
  • ApoE (apolipoprotein E)
  • CETP (cholesteryl ester transfer protein)
  • SELE (selectin E)
These genes affect how the body breaks down and clears fats and how cholesterol is processed. They also affect lipid balance, plaque formation, and blood vessel integrity and function. Methylation
  • MTHFR (methylenetetrahydrofolate reductase)
Polymorphisms of this enzyme can disrupt the metabolism of homocysteine, resulting in its accumulation as well as impaired methylation. The presence of these SNPs can increase risk of cardiovascular disease,blood vessel damage, thrombosis (blood clots), stroke, and degenerative aging. Hypertension
  • GNB3 (guanine nucleotide-binding protein)
  • AGTR1 (angiotensin II receptor-1)
Polymorphisms of these genes are associated with blood vessel constriction, sodium and water retention, obesity, and increased susceptibility to hypertension. Coagulation
  • Factor 2 (prothrombin)
  • Factor 5 (Leiden)
  • PAI-1 (Plasminogen activator inhibitor-1)
  • GP3a (Glycoprotein 3)
These genetic variants can over-activate blood clotting processes, increasing the risk of sudden cardiac events such as thrombosis, heart attacks, and strokes. Test Type: Saliva Test Please contact us for pricing




Weight and Body Composition


Learn how your DNA influences your weight and body composition Genetic Weight Muscle Composition Saturated Fat and Weight Please contact us for pricing




Traits


Learn how your DNA influences your facial features, taste, smell and other traits. Asparagus Odor Detection Back Hair (available for men only) Bald Spot (available for men only) Bitter Taste Cheek Dimples Cleft Chin Earlobe Type Earwax Type Eye Color Finger Length Ratio Freckles Hair Texture Light or Dark Hair Early Hair Loss (available for men only) Newborn Hair Photic Sneeze Reflex Red Hair Skin Pigmentation Sweet vs. Salty Toe Length Ratio Unibrow Widow's Peak Please contact us for pricing




Genetic Health Risk


Learn how your genetics can influence your risk for certain diseases.Age-Related Macular Degeneration 2 variants in the ARMS2 and CFH genes; relevant for European descent Alpha-1 Antitrypsin Deficiency 2 variants in the SERPINA1 gene; relevant for European descent Celiac Disease 2 variants near the HLA-DQB1 and HLA-DQA1 genes; relevant for European descent Hereditary Hemochromatosis (HFE‑Related) 2 variants in the HFE gene; relevant for European descent Hereditary Thrombophilia 2 variants in the F2 and F5 genes; relevant for European descent Late-Onset Alzheimer's Disease 1 variant in the APOE gene; variant found and studied in many ethnicities Parkinson's Disease 2 variants in the LRRK2 and GBA genes; relevant for European, Ashkenazi Jewish, North African Berber descent Please contact us for pricing




Sleep


Caffeine and its Effect on Sleep Deep Sleep Sleep Movement Please contact us for pricing




Syndrome and Diseases Carrier Status Reports


If you are starting a family, find out if you are a carrier for certain inherited conditions. ARSACS 1 variant in the SACS gene; relevant for French Canadian descent Agenesis of the Corpus Callosum with Peripheral Neuropathy 1 variant in the SLC12A6 gene; relevant for French Canadian descent Autosomal Recessive Polycystic Kidney Disease 3 variants in the PKHD1 gene Beta Thalassemia and Related Hemoglobinopathies 10 variants in the HBB gene; relevant for Sardinian, Cypriot, Italian/Sicilian, Greek descent Bloom Syndrome 1 variant in the BLM gene; relevant for Ashkenazi Jewish descent Canavan Disease 3 variants in the ASPA gene; relevant for Ashkenazi Jewish descent Congenital Disorder of Glycosylation Type 1a (PMM2-CDG) 2 variants in the PMM2 gene; relevant for Danish descent Cystic Fibrosis 29 variants in the CFTR gene; relevant for Ashkenazi Jewish, European, Hispanic/Latino descent D-Bifunctional Protein Deficiency 2 variants in the HSD17B4 gene Dihydrolipoamide Dehydrogenase Deficiency 1 variant in the DLD gene; relevant for Ashkenazi Jewish descent Familial Dysautonomia 1 variant in the IKBKAP gene; relevant for Ashkenazi Jewish descent Familial Hyperinsulinism (ABCC8-Related) 3 variants in the ABCC8 gene; relevant for Ashkenazi Jewish descent Fanconi Anemia Group C 3 variants in the FANCC gene; relevant for Ashkenazi Jewish descent GRACILE Syndrome 1 variant in the BCS1L gene; relevant for Finnish descent Gaucher Disease Type 1 3 variants in the GBA gene; relevant for Ashkenazi Jewish descent Glycogen Storage Disease Type Ia 1 variant in the G6PC gene; relevant for Ashkenazi Jewish descent Glycogen Storage Disease Type Ib 2 variants in the SLC37A4 gene Hereditary Fructose Intolerance 4 variants in the ALDOB gene; relevant for European descent Herlitz Junctional Epidermolysis Bullosa (LAMB3-Related) 3 variants in the LAMB3 gene Leigh Syndrome, French Canadian Type 1 variant in the LRPPRC gene; relevant for French Canadian descent Limb-Girdle Muscular Dystrophy Type 2D 1 variant in the SGCA gene Limb-Girdle Muscular Dystrophy Type 2E 1 variant in the SGCB gene; relevant for Amish descent Limb-Girdle Muscular Dystrophy Type 2I 1 variant in the FKRP gene MCAD Deficiency 4 variants in the ACADM gene; relevant for European descent Maple Syrup Urine Disease Type 1B 2 variants in the BCKDHB gene; relevant for Ashkenazi Jewish descent Mucolipidosis Type IV 1 variant in the MCOLN1 gene; relevant for Ashkenazi Jewish descent Neuronal Ceroid Lipofuscinosis (CLN5-Related) 1 variant in the CLN5 gene; relevant for Finnish descent Neuronal Ceroid Lipofuscinosis (PPT1-Related) 3 variants in the PPT1 gene; relevant for Finnish descent Niemann-Pick Disease Type A 3 variants in the SMPD1 gene; relevant for Ashkenazi Jewish descent Nijmegen Breakage Syndrome 1 variant in the NBN gene Nonsyndromic Hearing Loss and Deafness, DFNB1 (GJB2-Related) 2 variants in the GJB2 gene; relevant for Ashkenazi Jewish, European descent Pendred Syndrome and DFNB4 Hearing Loss (SLC26A4-Related) 6 variants in the SLC26A4 gene Phenylketonuria and Related Disorders 23 variants in the PAH gene; relevant for Irish, Northern European descent Primary Hyperoxaluria Type 2 1 variant in the GRHPR gene Rhizomelic Chondrodysplasia Punctata Type 1 1 variant in the PEX7 gene Salla Disease 1 variant in the SLC17A5 gene; relevant for Finnish, Swedish descent Sickle Cell Anemia 1 variant in the HBB gene; relevant for African American, African descent Sjögren-Larsson Syndrome 1 variant in the ALDH3A2 gene; relevant for Swedish descent Tay-Sachs Disease 4 variants in the HEXA gene; relevant for Ashkenazi Jewish, Cajun descent Tyrosinemia Type I 4 variants in the FAH gene; relevant for French Canadian, Finnish descent Usher Syndrome Type 1F 1 variant in the PCDH15 gene; relevant for Ashkenazi Jewish descent Usher Syndrome Type 3A 1 variant in the CLRN1 gene; relevant for Ashkenazi Jewish descent Zellweger Syndrome Spectrum (PEX1-Related) 1 variant in the PEX1 gene Please contact us for pricing




Pharmacogenonics (Personalised Medicine)


Pharmacogenetics studies our predisposition to drugs. Thanks to this DNA analysis we can know if we are predisposed to a drug that can be toxic to us, or that it has little effect, or too much effect, and much more. We have always observed how some drugs do the desired effect for some people and yet others do not. There may be many causes that explain these differences, and pharmacogenetics is undoubtedly one of the most important factors. Our DNA analysis of pharmacogenetics analyzes a list of medicines from our genetic map. We are based on consolidated scientific studies and widely accepted by the scientific community to which we apply your genetic data. Once you cross your genetic data with these studies, our algorithms show us the predisposition of each one to these drugs. Personalized medicine Every time we talk more about personalized medicine or precision medicine, pharmacogenetics is the first step in individualized medicine where it is no longer prescribed in an industrialized way; where no wrong drugs are no longer prescribed when, with the genetic data in hand, we know that they are not the most indicated for us. In the new era of personalized medicine, each person is given his drugs, because no two people are the same and the drugs feel differently to each one of us. Thanks to DNA analysis of pharmacogenomics we can know our predisposition to several drugs, so that doctors can avoid those that we know that it is very likely that they produce toxicity or that simply will not make the desired effect. The doctors will be able to choose the drugs that best suit us and calculate the doses in a much smarter way. Personalized medicine is, at the same time, a fundamental element for saving costs (and time) for healthcare systems, because the "let's try this medication and if it does not work we'll change it" is reduced consistently. There are medications that, once prescribed, take months to evaluate whether they are making the desired effect or not. In many cases, for the same pathology there are different pharmacological alternatives, and our doctor, having our pharmacological report, will have more chances of hitting the first one. Our pharmacogenetic report is divided into 5 medical specialties: Cardiology, Neurology, Pain, Oncologylogy and Others. Please contact us for pricing




Skin


Your skin is one of the most important organs you have, not to mention the largest! Looking after it is just as key as looking after your insides, but many people often forget about it. With our DNA Skin Test, you can refocus and learn how to protect this vital part of your body as within in our results you’ll find out things about how you can keep your skin looking and feeling great. Skin Ageing Is your skin sensitive to ageing from the sugar in your diet, the pollution in your environment or UV from the sun? Skin Elasticity Are you more likely to develop stretch marks and cellulite than others, and what can you do about it? Skin Moisture Could you be carrying genetic markers associated with dry skin? Could this be having a pronounced effect on your skin’s own natural moisture level? Knowing this can help you to optimise your skin care regime. UV Sensitivity Our DNA Skin Test can help you understand if your genetics may be making you more susceptible to UV damage and advise what steps can you take to avoid damaging your skin and avoiding long term health risks. Please contact us for pricing




Nutrition & Metabolism


Many times we have seen that not everyone feels the food in the same way. Some times we see someone loosing weight while we remain the same having the same food and doing the same exercise. Every human being is different and many of these answers are in our genes.Whether if we want to feed ourselves in the healthiest way possible, or if we want to lose weight, performing this nutrition genetic test is the best start. We will be able to know things as basic as, for example, what nutrients we should increase, since we have a genetic predisposition to not to assimilate them as effectively as other people. There are small genetic variants that makes metabolize certain vitamins and minerals very poorly, so our body will need a larger amount to meet our daily needs. We'll see some of that in our genes. It happens the same with many other nutrients, we may have different reactions to certain types of fats, or carbohydrates, etc.Thanks to the genetic analysis, you can know more about yourself, why caffeine is different for you and than others or why you like more sweets, or you can not feel certain flavors ... If you are worried about losing weight, your genetic information will help you a lot. We will be able to see your predisposition about which type of slimming diet will be most effective. There are genes that can show certain tendencies to gain weight, to feel satiated and the desire to eat. We can see if you are predisposed to lose weight more easily and we will see what the genes say about what could be the most effective way to lose weight and feel better than ever.Find what your DNA says about your requirements and sensitivies to different food groups.

  • Gluten Intolerance Risk
  • Iron Requirements
  • Lactose Intolerance Risk
  • Alcohol Flush Reaction
  • Antioxidant Requirements
  • Caffeine Sensitivity
  • Carbohydrate Sensitivity
  • Eating Behavior
  • Polyunsaturated Fat Sensitivity
  • Vitamin A Requirements
  • Vitamin D Requirements
  • Vitamin E Requirements
  • Vitamin B6 Requirements
  • Vitamin B9 Requirements
  • Vitamin B12 Requirements
  • Vitamin C Requirements
  • Salt Sensitivity
  • Saturated Fat Sensitivity
Please contact us for pricing




Sports & Fitness


To get to the top to train hard is not enough, you have to train smart. Knowing yourself is the best starting point. Our genetic study for the sport is, today, the most complete on the market. It will give you the key data for planning your training in the most intelligent way.

It will help you to reach your goals and avoid injuries.Sports Sample Report "Everything is written in our genes"Buy NowThis DNA Performance Test has the following sections:

Sport Profile

We will analyze your genes predisposition to be more brilliant in resistance or explosiveness sport. We will analyze the aerobic capacity (VO2max) written in your genes, as well as other abilities oriented to the sport.

Muscular Profile

We will see the predisposition of your muscles to the strength workouts; We can see what your genes say about the fatigue resistance of your muscles , and we can even assess the ability of the muscle to regenerate himself according to your genetic code.

Metabolic Profile

Not everyone has equal repercussions on sports and the same effects. In your genetic code we can see the global predisposition of the benefits of sport in your body; How you are predisposed to lose weight, the sensitivity of insulin in the performance of the sport and even what is your predisposition regarding the reduction of cholesterol with exercise.

Cardiovascular Profile

We can see what are your genes saying about how your blood pressure can react when practicing spors, and even what is your predisposition to get it to lower levels through regular exercise. We can see your genetic response to HDL cholesterol on sports, and how easy you can reduce your average heart rate thanks to exercising. Injury Risk Several studies have associated certain genotypes to have a predisposition greater than normal to suffer certain types of injuries, both joints and other types of injury. We can tell you the predisposition expressed in certain genes associated with greater fragility in the ligaments, and other specific pathologies like the Achilles tendon.

  • Aerobic Capacity (VO2 Max)

  • Endurance

  • Sprinting

  • Anaerobic/Lactate Threshold

  • Flexibility

  • Injury and repair

  • Muscle fatigue resistance

  • Fat loss in response to exercise

  • Resistance training and muscle building

Please contact us for pricing




Fitness


Aerobic Capacity (VO2 Max)

Endurance

Sprinting

Anaerobic/Lactate Threshold

Flexibility

Injury and repair

Muscle fatigue resistance

Fat loss in response to exercise

Resistance training and muscle building

Please contact us for pricing




Ancestry


Discover where your DNA is from out of 150+ regions worldwide - and more. Ancestry Composition Maternal Haplogroup Paternal Haplogroup Neanderthal Ancestry Your DNA Family Please contact us for pricing




Personality & Learning


Explore the role your DNA plays in your personality traits, learning predispositions, and genetically-influenced personality profiles and interpersonal tendencies.

  • Personality Profile
  • Interpersonal Characteristics
  • Learning Personality
Please contact us for pricing





Contact

© 2018 Lifestyle & Innovation, Fitness Therapies

30 Park View Road

Ealing, London, W52JB

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Tel: 07951365567

info@LIFTclinic.co.uk

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